There are 8 ways to get from Lyon to Mannheim by train (TGV), bus, car, plane, train, or train (TGV, Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (TGV)
best- Take the train from Lyon Part Dieu to Mannheim Hbftrain Tgv
5h 16m€120–180Bus
cheapest- Take the bus from Lyon to Mannheim central bus stationbus N7720 / ...
9h 35m€50–85Drive 598.6 km
- Drive from Lyon to Mannheimcar 598.6 km
5h 56m€110–159Fly Lyon–Saint Exupéry Airport to Frankfurt, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Frankfurt (FRA)plane LYS - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
4h 56m€144–357Train via Basel
- Take the train from Lyon Part Dieu to Genevetrain Ter
- Take the train from Genève to Renens VDtrain Ic1 / ...
- Take the train from Renens VD to Basel SBBtrain
- Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain 12 / ...
8h 26m€140–293Fly Lyon–Saint Exupéry Airport to Strasbourg International Airport, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Strasbourg International Airport (SXB)plane LYS - SXB
- Take the train from Strasbourg to Mannheim Hbftrain
5h 9m€137–339Train to Geneva International Airport, fly to Frankfurt, train
- Take the train from Lyon Part Dieu to Genevetrain
- Fly from Geneva International Airport (GVA) to Frankfurt (FRA)plane GVA - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
6h 41m€152–343Fly Lyon–Saint Exupéry Airport to Stuttgart Airport, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Stuttgart Airport (STR)plane LYS - STR
- Take the train from Hauptbahnhof to Mannheim, Hauptbahnhoftrain
7h 26m€141–374
Lyon to Mannheim by train (TGV)
Comparing Your Travel Options
The cheapest way to get from Lyon to Mannheim is to bus which costs €50 - €85 and takes 9h 35m.
The fastest way to get from Lyon to Mannheim is to fly and train which takes 4h 56m and costs €140 - €360.
Yes, there is a direct bus departing from Lyon and arriving at Mannheim central bus station station. Services depart four times a day, and operate every day. The journey takes approximately 9h 35m.
Yes, there is a direct train departing from Lyon Part Dieu and arriving at Mannheim Hbf. Services depart twice daily, and operate every day. The journey takes approximately 5h 16m.
The distance between Lyon and Mannheim is 640 km. The road distance is 598.6 km.
The best way to get from Lyon to Mannheim without a car is to train which takes 5h 16m and costs €120 - €180.
The train from Lyon Part Dieu to Mannheim Hbf takes 5h 16m including transfers and departs twice daily.
Lyon to Mannheim bus services, operated by FlixBus, depart from Lyon station.
Lyon to Mannheim train services, operated by TGV inOui, depart from Lyon Part Dieu station.
The best way to get from Lyon to Mannheim is to train which takes 5h 16m and costs €120 - €180. Alternatively, you can bus, which costs €50 - €85 and takes 9h 35m.
What companies run services between Lyon, France and Mannheim, Germany?
TGV inOui operates a train from Lyon Part Dieu to Mannheim Hbf twice daily. Tickets cost €120–180 and the journey takes 5h 16m. Alternatively, FlixBus operates a bus from Lyon to Mannheim central bus station 3 times a day. Tickets cost €55–85 and the journey takes 9h 35m. BlaBlaCar Bus also services this route twice daily.
- Website
- lufthansa.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €60–460
Flights from Lyon–Saint Exupéry Airport to Frankfurt via Munich
- Ave. Duration
- 3h 18m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- €65–370
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- €100–460
Flights from Geneva International Airport to Frankfurt via Munich
- Ave. Duration
- 3h 5m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- €100–240
Flights from Lyon–Saint Exupéry Airport to Stuttgart Airport via Munich
- Ave. Duration
- 4h 45m
- When
- Sunday, Monday, Tuesday, and Wednesday
- Estimated price
- €60–480
- Website
- swiss.com
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- €100–460
Flights from Geneva International Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- €100–240
- Website
- airbus.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €60–200
- Website
- brusselsairlines.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt via Brussels
- Ave. Duration
- 3h 40m
- When
- Monday, Wednesday, Friday, Saturday, and Thursday
- Estimated price
- €60–230
Flights from Geneva International Airport to Frankfurt via Brussels
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- €200–260
- Website
- klm.com
Flights from Lyon–Saint Exupéry Airport to Stuttgart Airport via Amsterdam Schiphol
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- €75–420
- Website
- airdolomiti.it
Flights from Lyon–Saint Exupéry Airport to Frankfurt
- Ave. Duration
- 1h 25m
- When
- Monday to Saturday
- Estimated price
- €130–460
Flights from Geneva International Airport to Frankfurt
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €130–460
- Website
- twinjet.fr
Flights from Lyon–Saint Exupéry Airport to Strasbourg International Airport
- Ave. Duration
- 1h 10m
- When
- Monday to Friday
- Estimated price
- €470–1,000
- Website
- airfrance.com
Flights from Lyon–Saint Exupéry Airport to Frankfurt via Paris Charles de Gaulle
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €45–280
- Website
- austrian.com
Flights from Lyon–Saint Exupéry Airport to Stuttgart Airport via Vienna
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- €100–450
- Website
- lufthansa-city.com
Flights from Lyon–Saint Exupéry Airport to Stuttgart Airport via Munich
- Ave. Duration
- 6h 45m
- When
- Sunday
- Estimated price
- €60–370
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Lyon Part Dieu to Mannheim Hbf
- Ave. Duration
- 5h 16m
- Frequency
- Twice daily
- Estimated price
- €120–180
- Website
- TGV inOui
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- €30–45
- Website
- TGV inOui
Train from Strasbourg to Mannheim Hbf
- Ave. Duration
- 1h 22m
- Frequency
- 4 times a day
- Estimated price
- €27–40
- Website
- TGV inOui
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- €30–45
- Website
- TGV inOui
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €10–21
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 6m
- Frequency
- Hourly
- Estimated price
- €35–75
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Strasbourg to Mannheim Hbf
- Ave. Duration
- 1h 7m
- Frequency
- Every 4 hours
- Estimated price
- €20–40
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €10–21
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- €16–35
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- Every 4 hours
- Estimated price
- €8–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- Every 4 hours
- Estimated price
- €8–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Once daily
- Estimated price
- €12–22
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 2h 2m
- Frequency
- Hourly
- Estimated price
- €30–50
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 2h 2m
- Frequency
- Hourly
- Estimated price
- €30–50
- Website
- Oui.SNCF
Train from Genève to Renens VD
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €18–35
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Renens VD to Basel SBB
- Ave. Duration
- 2h 15m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Basel SBB to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 19m
- Frequency
- Twice daily
- Estimated price
- €55–110
- Website
- Trenitalia Eurocity
- 1st Class
- €75–110
- 2nd Class
- €55–80
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Lyon to Mannheim central bus station
- Ave. Duration
- 9h 35m
- Frequency
- 3 times a day
- Estimated price
- €55–85
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Lyon to Mannheim central bus station
- Ave. Duration
- 9h 20m
- Frequency
- Twice daily
- Estimated price
- €50–85
- Website
- BlaBlaCar Bus
Want to know more about travelling around Germany
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Booking & Getting There
Lyon to Mannheim bus services, operated by FlixBus, arrive at Mannheim central bus station.
Lyon to Mannheim train services, operated by TGV inOui, arrive at Mannheim Hbf station.
Yes, the driving distance between Lyon to Mannheim is 599 km. It takes approximately 5h 56m to drive from Lyon to Mannheim.
Book your Lyon to Mannheim train tickets online with Omio.
Book your Lyon to Mannheim bus tickets online with Omio and FlixBus.
There are 1502+ hotels available in Mannheim.













































