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How to get fromGuelph to Bostonby bus (Greyhound), bus, train, car, plane, or train (Amtrak)

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There are 6 ways to get from Guelph to Boston by bus (Greyhound), bus, train, car, plane, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Guelph Central GO Bus to Winston Churchill Transitway Stationbus bus 29
    2. Take the bus from Mississauga to Buffalobus bus
    3. Take the bus from Buffalo to Bostonbus bus
    15h 59m
    $106–193

  2. Drive  541.8 mi

    cheapest
    1. Drive from Guelph to Bostoncar car 541.8 mi
    9h 50m
    $104–150

  3. Bus, train

    1. Take the bus from Guelph Central GO Bus to Aldershot GO Busbus bus 17
    2. Take the train from Aldershot to Buffalotrain train
    3. Take the train from Buffalo Depew Station to Bostontrain train
    18h 8m
    $286–587

  4. Train, fly

    1. Take the train from Guelph Central GO to Union Station GOtrain train
    2. Fly from Toronto Island Airport (YTZ) to Laguardia Airport (LGA)plane plane YTZ - LGA
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    10h 36m
    $682–1,529

  5. Train

    1. Take the train from Guelph Central GO to Union Station GOtrain train Ki
    2. Take the train from Toronto to Canadian Bordertrain train
    3. Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain train
    4. Take the train from Buffalo Depew Station to Bostontrain train
    18h 35m
    $321–649

  6. Train, bus

    1. Take the train from Guelph Central GO to Union Station GOtrain train Ki
    2. Take the bus from Toronto to Ithacabus bus
    3. Take the bus from Ithaca to Bostonbus bus
    18h 45m
    $108–164

Guelph to Boston by bus

Calendar7Weekly Buses
Duration15h 59mAverage Duration
Ticket$106Cheapest Price
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Comparing Your Travel Options

Map of how to get from Guelph to Boston.ExpandLaunch map view
  • Distance: 590.9 mi
  • Duration: 15h 59m

What companies run services between Guelph, ON, Canada and Boston, MA, USA?

You can take a bus from Guelph Central GO Bus to Boston via Winston Churchill Transitway Station, Mississauga, and Buffalo in around 15h 59m. Alternatively, you can take a train from Guelph Central GO to Boston via Toronto, Canadian Border, Niagara Falls Amtrak Station, and Buffalo Depew Station in around 18h 35m.

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Need to know: Greyhound

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